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华蟾蜍精
Cinobufagin
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086074 | 5 mg | 1010 | |||
4086074 | 25 mg | 3510 |
产品别名
470-37-1
华蟾蜍精
Cinobufagin
5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate
14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate, 5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate
14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C26H34O6 |
Molecular weight | 442.54 |
MDL number | MFCD00056825 |
Biochem/physiol Actions【生化/生理作用】 | Cinobufagin is a bufanolide steroid with anti-proliferative and pro-apoptotic effects as well as antinociception activity. It has been used in Chinese herbal medicine and has been shown to have clinical applications in a variety of cancers both as an anticancer agent and to reduce cancer pain. Cinobufagin was recently identified as novel expression-mimicker that exert in vitro as well as in vivo anti-AML efficacy against AML expressing mtRUNX1. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
SMILES string | C[C@]([C@@H](C(C=C1)=COC1=O)[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@H](O)C5)C)[C@@]64[C@@H]2O6 |
InChI | 1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1 |
InChI key | SCULJPGYOQQXTK-OLRINKBESA-N |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H300 + H310 + H330 |
Precautionary Statements | P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310 |
Hazard Classifications【危险分类】 | Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral |
Storage Class Code【储存分类代码】 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
WGK | WGK 3 |