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BAY-899
产品别名
2471967-92-5
BAY-899
(5S)-N-[2-(4-Fluorophenoxy)pyrimidin-5-yl]-5-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxamide
(S)-N-(2-(4-Fluorophenoxy)pyrimidin-5-yl)-5-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxamide
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C25H19F2N5O2 |
Molecular weight | 459.45 |
MDL number | MFCD32263051 |
Biochem/physiol Actions【生化/生理作用】 | BAY-899 is an orally available, potent and selective antagonist of the human luteinizing hormone receptor (hLH-R) that reduces sex hormone levels in several animal models. BAY-899 likely binds to a putative rhodopsin-like binding cavity located within the 7-transmembrane region of the hLH-receptor. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
optical activity【旋光性】 | [α]/D 165 to 195°, c = 1 in chloroform-d |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 1 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O=C(N1[C@@H](C2=CC=C(F)C=C2)C3=C(N=CC=C3)CC1)NC4=CN=C(OC5=CC=C(F)C=C5)N=C4 |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |