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AS3334034
产品别名
AS3334034
7-Methoxy-6-(2-methylpropane-2-sulfonyl)-N-(4-methyl-1H-pyrazol-3-yl)quinolin-4-amine
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H22N4O3S |
Molecular weight | 374.46 |
Biochem/physiol Actions【生化/生理作用】 | AS3334034 is an orally available, potent and selective RIP2 (Receptor-interacting protein kinase 2) inhibitor that exhibits renoprotective effects in uninephrectomized adriamycin-induced CKD (chronic kidney disease) rats. It appears that AS3334034 suppresses the progression of chronic renal failure via an anti-inflammatory effect. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | CC1=CNN=C1NC2=CC=NC3=CC(OC)=C(S(=O)(C(C)(C)C)=O)C=C32 |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |