Anti-MLL/HRX Antibody, NT., clone N4.4

32160702

NA.41

The acute lymphoblastic leukaemia (ALL)-1 (also known as MLL, HRX, HTRX, and TRX1) gene on human chromosome 11q23 is the site of many locally clustered chromosomal alterations associated with several types of acute leukaemias, including deletions, partial duplications and translocations. Structurally variant proteins derived from the altered gene presumably cause the malignant transformation of early haemopoietic progenitor cells.

Recognizes N-terminal proteolytic fragment of MLL (MLLN).

MBP fusion protein corresponding to residues 161-356 of human mixed lineage leukemia, MLL

Detect MLL/HRX with Anti-MLL/HRX Antibody, N-term., clone N4.4 (Mouse Monoclonal Antibody), that has been shown to work in IP & WB.

routinely evaluated by immunoblot on nuclear extract from K562 cells

Immunoaffinity Purified immunoglobulin in 0.014M phosphate buffer, pH 7.6, 0.175M NaCl, 0.07% sodium azide, and 30% glycerol.
Protein G Purified
Format: Purified

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

affinity purified immunoglobulin

primary antibodies

N4.4, monoclonal

mouse, human

Upstate^®

immunoprecipitation (IP): suitable
western blot: suitable

IgG1

NM_005933

Q03164

wet ice

300 kDa

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10 - Combustible liquids

WGK 1