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C4 Ceramide (d18:1/4:0)

产品编号:4084785
规格:N-butyroyl-D-erythro-sphingosine, powder
CAS NO:74713-58-9
包装规格:5 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40847855 MG1130
产品别名

74713-58-9

C4 Ceramide (d18:1/4:0)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H43NO3
Molecular weight
369.58
NACRES
NA.25
General description【一般描述】
C4 Ceramide (d18:1/4:0) or N-butyroyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with butyric acid. It is a non-toxic, short-chain sphingolipid.
Application【应用】
C4 Ceramide (d18:1/4:0) has been used to study its role in rescuing and stabilizing ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).
Biochem/physiol Actions【生化/生理作用】
C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF).
产品性质
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 860504P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
OC[C@]([H])(NC(CCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
packaging【包装】
5 mL Amber Glass Screw Cap Vial (860504P-5mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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