您的位置：首页 > 产品中心 > Anti-Nucleolin Antibody, clone 3G4B2
Anti-Nucleolin Antibody, clone 3G4B2
| 产品编号： | 4084693 |
| 规格： | culture supernatant, clone 3G4B2, Upstate® |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Nucleolin, also known as C23, is the major nucleolar protein of exponentially growing eukaryotic cells. It is a ubiquitous conserved multi-domain phosphoprotein found in all vertebrate species. Nucleolin contains a specific bipartite nuclear localization signal sequence and three different structural domains. Nucleolin is a multifunctional protein involved in most steps of ribosome biogenesis. Nucleolin has been implicated in chromatin structure, rDNA transcription, rRNA maturation, ribosome assembly, cytokinesis, nucleogenesis, cell proliferation and growth, and nucleo-cytoplasmic transport. Nucleolin also exhibits autodegradation, DNA and RNA helicase activities, and DNA-dependent ATPase activity. Nucleolin activities may be regulated by proteolysis, methylation, ADPribosylation, and phosphorylation by several kinases, including casein kinase II (CK2), p34cdc2, and protein kinase C-ζ. |
| Specificity【特异性】 | nucleolin |
| Immunogen【免疫原】 | Nuclear matrix extract from MDCK cells |
| Application【应用】 | Anti-Nucleolin Antibody, clone 3G4B2 is a high quality Mouse Monoclonal Antibody for the detection of Nucleolin & has been validated in IP, WB, ICC. |
| Quality【质量】 | routinely evaluated by immunoblot on HeLa nuclear extract |
| Linkage【联系】 | Replaces: MABE466 |
| Physical form【外形】 | mouse culture supernatant containing 0.05% sodium azide prior to the addition of glycerol to 30% Unpurified |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | culture supernatant |
| antibody product type | primary antibodies |
| clone【克隆】 | 3G4B2, monoclonal |
| species reactivity | canine, human, monkey |
| manufacturer/tradename | Upstate® |
| technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NM_005381 |
| UniProt accession no.【UniProt登记号】 | P19338 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... NCL(4691) |
产品说明
| Target description【目标描述】 | 100kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
