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Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10

产品编号:4084610
规格:ascites fluid, clone 3HH4-4C10, from mouse
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4084610100 μL6690
产品别名

Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10

H4KAc, Histone H4 (acetyl), H4 histone family, member N, H4 histone, family 2, histone 2, H4, histone 2, H4a, histone IV, family 2, histone cluster 2, H4a

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Posttranslational acetylation of the conserved core histone N-terminal tail domains is typically associated with gene activation.
Specificity【特异性】
This antibody recognizes Histone H4.
Immunogen【免疫原】
Linear peptide corresponding to human Histone H4 acetylated at Lys5/8/12/16.
Epitope: Lys5/8/12/16
Application【应用】
Immunocytochemistry Analysis:
1:500 dilution from a representative lot detected Histone H4 in A431 and HeLa cells.
Use Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10 (mouse monoclonal antibody) validated in WB, ICC to detect acetyl Histone H4 (Lys5/8/12/16) also known as H4KAc, Histone H4 (acetyl).
Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function
Quality【质量】
Evaluated by Western Blot in HeLa acid extract lysate.

Western Blot Analysis: 1:2,000 dilution of this antibody detected Histone H4 on 10 µg of HeLa acid extract lysate.
Physical form【外形】
Unpurified
Unpurified mouse monoclonal IgG1κ preservative-free ascites.
Analysis Note【分析说明】
Control
HeLa acid extract lysate
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
3HH4-4C10, monoclonal
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype【同位素/亚型】
IgG1κ
NCBI accession no.【NCBI登记号】
NP_778224
UniProt accession no.【UniProt登记号】
P62805
shipped in【运输】
dry ice
产品说明
Target description【目标描述】
~ 13 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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