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PKCε Translocation Inhibitor Peptide-Calbiochem
产品编号: | 4084137 |
规格: | The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
PKCε Translocation Inhibitor Peptide-Calbiochem
Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
基本信息
Empirical Formula【经验(实验)分子式】 | C37H65N9O13 |
Molecular weight | 843.96 |
General description【一般描述】 | An octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes. An octapeptide that selectively inhibits the translocation of PKCε to subcellular sites. Inhibition of PKCε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes. |
Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: yes Primary Target PKCε Translocation Cell permeable: no |
Warning【警告】 | Toxicity: Standard Handling (A) |
Sequence【序列】 | H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH |
Physical form【外形】 | Supplied as a trifluoroacetate salt. |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C. |
Other Notes【其他说明】 | Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417. Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962. |
Legal Information【法律信息】 | Sold under license of U.S. Patent 5,783,405. CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | lyophilized solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
color【颜色】 | white |
solubility【溶解性】 | water: 3 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |