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p-APMSF, Hydrochloride-CAS 74938-88-8-Calbiochem
产品编号: | 4084122 |
规格: | Alternative to DFP and PMSF. |
CAS NO: | 74938-88-8 |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4084122 | 5 MG | 2380 |
产品别名
74938-88-8
p-APMSF, Hydrochloride-CAS 74938-88-8-Calbiochem
p-Amidinophenylmethylsulfonylfluoride, HCl
基本信息
MDL number | MFCD00078902 |
General description【一般描述】 | Alternative to DFP and PMSF. An irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentration. Acts on C1r, C1s, Factor Xa, and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF. An alternative to DFP and PMSF. Specific irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentrations. Acts on C1r, C1s, Factor Xa and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF. Stability is pH dependent: t½ = 20 min at pH 6.0; 6 min at pH 7.0; 1 millisecond at pH 8.0. |
Biochem/physiol Actions【生化/生理作用】 | Primary Target trypsin-like serine proteases Product does not compete with ATP. Reversible: no Cell permeable: no |
Warning【警告】 | Toxicity: Standard Handling (A) |
Reconstitution【重悬】 | Unstable in solution; reconstitute just prior to use. |
Other Notes【其他说明】 | Cole, T.C., et al. 1989. Biochim. Biophys. Acta 990, 254. Laura, R., et al. 1980. Biochemistry19, 4859. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated |
color【颜色】 | white |
solubility【溶解性】 | water: 25 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H |
InChI key | KHLLRHIUKOJXLL-UHFFFAOYSA-N |
packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |