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Nitric Oxide Synthase, Neuronal Inhibitor I-CAS 357965-99-2-Calbiochem
产品编号: | 4084120 |
规格: | The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications. |
CAS NO: | 357965-99-2 |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
357965-99-2
Nitric Oxide Synthase, Neuronal Inhibitor I-CAS 357965-99-2-Calbiochem
(4S)-N-(4-Amino-5[aminoethyl]aminopentyl)-N'-nitroguanidine, TFA
基本信息
Empirical Formula【经验(实验)分子式】 | C8H21N7O2 · 3C2HF3O2 · 2H2O |
Molecular weight | 625.40 |
MDL number | MFCD05865227 |
General description【一般描述】 | A cell-permeable, potent, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS) (Ki = 120 nM). Displays >2,500-fold and 192-fold selectivity over eNOS and iNOS, respectively. A cell-permeable, potent and highly selective inhibitor of neuronal nitric oxide synthase (nNOS); (Ki = 120 nM). Displays >2500-fold and 320-fold selectivity over eNOS and iNOS, respectively. |
Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Cell permeable: yes Reversible: no Primary Target nNOS Target Ki: 120 nM against nNOS |
Warning【警告】 | Toxicity: Standard Handling (A) |
Physical form【外形】 | Supplied as a dihydrate. |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Other Notes【其他说明】 | Hah, J.M., et al. 2001. J. Med. Chem.44, 2667. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
color【颜色】 | white to off-white |
solubility【溶解性】 | water: 1 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |