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Nitric Oxide Synthase, Neuronal Inhibitor I-CAS 357965-99-2-Calbiochem

产品编号:4084120
规格:The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
CAS NO:357965-99-2
包装规格:5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40841205 MG8040
产品别名

357965-99-2

Nitric Oxide Synthase, Neuronal Inhibitor I-CAS 357965-99-2-Calbiochem

(4S)-N-(4-Amino-5[aminoethyl]aminopentyl)-N'-nitroguanidine, TFA

基本信息
Empirical Formula【经验(实验)分子式】
C8H21N7O2 · 3C2HF3O2 · 2H2O
Molecular weight
625.40
MDL number
MFCD05865227
General description【一般描述】
A cell-permeable, potent, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS) (Ki = 120 nM). Displays >2,500-fold and 192-fold selectivity over eNOS and iNOS, respectively.
A cell-permeable, potent and highly selective inhibitor of neuronal nitric oxide synthase (nNOS); (Ki = 120 nM). Displays >2500-fold and 320-fold selectivity over eNOS and iNOS, respectively.
Biochem/physiol Actions【生化/生理作用】
Product does not compete with ATP.
Cell permeable: yes
Reversible: no
Primary Target
nNOS
Target Ki: 120 nM against nNOS
Warning【警告】
Toxicity: Standard Handling (A)
Physical form【外形】
Supplied as a dihydrate.
Reconstitution【重悬】
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes【其他说明】
Hah, J.M., et al. 2001. J. Med. Chem.44, 2667.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
desiccated (hygroscopic)
protect from light
color【颜色】
white to off-white
solubility【溶解性】
water: 1 mg/mL
shipped in【运输】
ambient
storage temp.【储存温度】
−20℃
packaging【包装】
5 mg in Plastic ampoule
Packaged under inert gas
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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