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MMP-3 Inhibitor I-Calbiochem
产品编号: | 4084112 |
规格: | The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
MMP-3 Inhibitor I-Calbiochem
Ac-RCGVPD-NH2, Stromelysin-1 Inhibitor
基本信息
Empirical Formula【经验(实验)分子式】 | C27H46N10O9S |
Molecular weight | 686.78 |
General description【一般描述】 | Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain. Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM). |
Biochem/physiol Actions【生化/生理作用】 | Primary Target MMP-3 Product does not compete with ATP. Target IC50: 5 µM against MMP-3 Reversible: no Cell permeable: no |
Warning【警告】 | Toxicity: Standard Handling (A) |
Sequence【序列】 | Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂ |
Physical form【外形】 | Supplied as a trifluroacetate salt. |
Reconstitution【重悬】 | Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C. |
Other Notes【其他说明】 | Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227. Hanglow, A.C., et al. 1993. Agents Actions 39, C148. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥90% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
color【颜色】 | white |
solubility【溶解性】 | water: 1 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |