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bpV(bipy)-Calbiochem
| 产品编号： | 4084003 |
| 规格： | A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
bpV(bipy)-Calbiochem
Potassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
基本信息
| Linear Formula【线性分子式】 | K[VO(O2)2C10H8N2] · 3H2O |
| General description【一般描述】 | A potent inhibitor of phosphotyrosine phosphatase activity (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM). A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM). |
| Biochem/physiol Actions【生化/生理作用】 | Target Ki: 100 nM for phosphotyrosine phosphatase Product does not compete with ATP. Primary Target phosphotyrosine phosphatase Reversible: no Cell permeable: no Target IC50: 18 nM against PTEN |
| Warning【警告】 | Toxicity: Harmful (C) |
| Reconstitution【重悬】 | Unstable in solution; reconstitute just prior to use. |
| Other Notes【其他说明】 | Schmid, A.C., et al. 2004. FEBS Lett.566, 35. Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (51V-NMR) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | yellow to orange |
| solubility【溶解性】 | water: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
