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IL-2Rα Antagonist-CAS 1217448-66-2-Calbiochem
| 产品编号： | 4083781 |
| 规格： | The IL-2Rα Antagonist, also referenced under CAS 1217448-66-2, controls the biological activity of IL-2Rα. |
| CAS NO： | 1217448-66-2 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
1217448-66-2
IL-2Rα Antagonist-CAS 1217448-66-2-Calbiochem
(R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H30N4O3 · xC2HF3O2 |
| Molecular weight | 446.54 (free base basis) |
| General description【一般描述】 | A non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC50 = 3 µM). |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Target IC50: 3 µM against IL-2/IL-2Rα interaction Primary Target Inhibitor of the IL-2/IL-2Rα interaction Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Emerson, S.D., et al. 2003. Protein Science12, 811. Tilley, J.W., et al. 1997. J. Am. Chem. Soc.119, 7589. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | ethanol: 2 mg/mL DMSO: 28 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
