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Anti-TLS Antibody, clone 1FU-1D2

产品编号:4082534
规格:ascites fluid, clone 1FU-1D2, from mouse
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4082534100 μL6020
产品别名

Anti-TLS Antibody, clone 1FU-1D2

75 kDa DNA-pairing protein, FUS-CHOP fusion protein, FUS-CHOP protein fusion, Fusion gene in myxoid liposarcoma, Oncogene FUS, Oncogene TLS, Translocated in liposarcoma protein, fus-like protein, fus/tls-chop oncogene, fusion (involved in t(12, 16) in ma

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
The TLS/FUS protein contains an RNA-recognition motif and is a component of nuclear riboprotein complexes. It resembles a transcription factor in that it binds DNA, contributes a transcriptional activation domain to the FUS-ERG oncoprotein, and interacts with several transcription factors in vitro. It binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. It may play a role in maintenance of genomic integrity.
Specificity【特异性】
This antibody recognizes TLS.
Immunogen【免疫原】
Linear peptide corresponding to human TLS.
Epitope: Unknown
Application【应用】
Research Sub Category
RNA Metabolism & Binding Proteins

Transcription Factors
Use Anti-TLS Antibody, clone 1FU-1D2 (Mouse Monoclonal Antibody) validated in WB, ICC to detect TLS also known as 75 kDa DNA-pairing protein, FUS-CHOP fusion protein.
Immunocytochemistry Analysis:
1:500 dilution from a representative lot detected TLS in C2C12 cells.
Research Category
Epigenetics & Nuclear Function

Epigenetics & Nuclear Function
Quality【质量】
Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected TLS on 10 µg of HepG2 cell lysate.
Physical form【外形】
Unpurified
Unpurified mouse monoclonal IgG1κ preservative-free ascites.
Analysis Note【分析说明】
Control
HepG2 cell lysate
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
ascites fluid
antibody product type
primary antibodies
clone【克隆】
1FU-1D2, monoclonal
species reactivity
human, mouse, rat
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype【同位素/亚型】
IgG1κ
NCBI accession no.【NCBI登记号】
NP_004951.1
UniProt accession no.【UniProt登记号】
P35637
shipped in【运输】
dry ice
Gene Information
human ... FUS(2521)
产品说明
Target description【目标描述】
Observed at 65 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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