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Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Balpha, Bbeta and Bgamma . The B′ (or B56) family consists of at least seven splice variantsderived from five genes. RNA′s for the two members of the B′′ family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B′ subunits are conserved from yeast to mammals. |
Specificity【特异性】 | Human PP2A, B subunit, B56 delta. This monoclonal antibody is the delta isoform for the B56 family of protein phosphatase 2A. |
Immunogen【免疫原】 | GST fusion protein corresponding to the N-terminus of human PP2A, B subunit, B56 delta |
Application【应用】 | Immunoblotting (1:500 to 1:2000) Optimal working dilutions must be determined by the end user Research Category Signaling This Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12 is validated for use in WB for the detection of PP2A. Research Sub Category Kinases & Phosphatases |
Physical form【外形】 | Purified mouse monoclonal IgG1 antibody in PBS with 0.05% NaN3. Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | H5D12, monoclonal |
species reactivity | human |
manufacturer/tradename | Upstate® |
technique(s) | western blot: suitable |
isotype【同位素/亚型】 | IgG1 |
NCBI accession no.【NCBI登记号】 | NM_006245 |
UniProt accession no.【UniProt登记号】 | Q14738 |
shipped in【运输】 | wet ice |
Gene Information | human ... PPP2R5D(5528) |
产品说明
Storage and Stability【储存及稳定性】 | Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |