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Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal

产品编号:4082510
规格:culture supernatant, clone N453, Upstate®
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4082510100 μL7860
产品别名

Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal

AMPA 1, AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1, glutamate receptor, ionotropic, AMPA 1

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors that have been divided into 3 groups. Group I includes GRM1 and these receptors have been shown to activate phospholipase C. GRM1 expression has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain and eye libraries.
Specificity【特异性】
Predicted cross-reactivity with human, mouse and chicken
Recognizes GluR1 phosphorylated on Serine 831.
Immunogen【免疫原】
KLH-conjugated, synthetic peptide containing the sequence ...QQ[pS]IN… in which pS corresponds to phospho-serine at position 831 of the GluR1 mature chain. Sequence is identical in human, rat, mouse and chicken.
Application【应用】
Western Blot Analysis:
A 1:1,000-1:4,000 dilution of this lot detected phosphorylated GluR1 from a rat brain microsomal preparation (Catalog # 12-144).

Research Category
Neuroscience
Anti-phospho-GluR1 (Ser831) Antibody, clone N453 detects level of phospho-GluR1 (Ser831) & has been published & validated for use in WB.
Research Sub Category
Neurotransmitters & Receptors
Quality【质量】
routinely evaluated by western blot
Linkage【联系】
Replaces: 05-823
Physical form【外形】
Cultured supernantant in 0.05% sodium azide.
Analysis Note【分析说明】
Control
Rat brain
Legal Information【法律信息】
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
culture supernatant
antibody product type
primary antibodies
clone【克隆】
N453, monoclonal
species reactivity
chicken, human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype【同位素/亚型】
IgG
NCBI accession no.【NCBI登记号】
NP_000818
UniProt accession no.【UniProt登记号】
P42261
shipped in【运输】
dry ice
Gene Information
human ... GRIA1(2890)
产品说明
Target description【目标描述】
106 kDa
Storage and Stability【储存及稳定性】
Stable for 1 year at -20°C from date of receipt.
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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