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Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal
产品编号: | 4082510 |
规格: | culture supernatant, clone N453, Upstate® |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal
AMPA 1, AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1, glutamate receptor, ionotropic, AMPA 1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors that have been divided into 3 groups. Group I includes GRM1 and these receptors have been shown to activate phospholipase C. GRM1 expression has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain and eye libraries. |
Specificity【特异性】 | Predicted cross-reactivity with human, mouse and chicken Recognizes GluR1 phosphorylated on Serine 831. |
Immunogen【免疫原】 | KLH-conjugated, synthetic peptide containing the sequence ...QQ[pS]IN… in which pS corresponds to phospho-serine at position 831 of the GluR1 mature chain. Sequence is identical in human, rat, mouse and chicken. |
Application【应用】 | Western Blot Analysis: A 1:1,000-1:4,000 dilution of this lot detected phosphorylated GluR1 from a rat brain microsomal preparation (Catalog # 12-144). Research Category Neuroscience Anti-phospho-GluR1 (Ser831) Antibody, clone N453 detects level of phospho-GluR1 (Ser831) & has been published & validated for use in WB. Research Sub Category Neurotransmitters & Receptors |
Quality【质量】 | routinely evaluated by western blot |
Linkage【联系】 | Replaces: 05-823 |
Physical form【外形】 | Cultured supernantant in 0.05% sodium azide. |
Analysis Note【分析说明】 | Control Rat brain |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | culture supernatant |
antibody product type | primary antibodies |
clone【克隆】 | N453, monoclonal |
species reactivity | chicken, human, mouse, rat |
manufacturer/tradename | Upstate® |
technique(s) | western blot: suitable |
isotype【同位素/亚型】 | IgG |
NCBI accession no.【NCBI登记号】 | NP_000818 |
UniProt accession no.【UniProt登记号】 | P42261 |
shipped in【运输】 | dry ice |
Gene Information | human ... GRIA1(2890) |
产品说明
Target description【目标描述】 | 106 kDa |
Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |