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Anti-Sox2, Alexa Fluor® 488 Conjugate Antibody

产品编号:4082422
规格:from rabbit, ALEXA FLUOR® 488
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4082422100 μL7020
产品别名

Anti-Sox2, Alexa Fluor® 488 Conjugate Antibody

Transcription factor SOX-2

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
SOX2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution.
Immunogen【免疫原】
Synthetic peptide from human Sox2.
Application【应用】
Research Category
Neuroscience
Research Sub Category
Transcription Factors
Detect Sox2 using this Anti-Sox2, Alexa Fluor 488 Conjugate Antibody validated for use in ICC.
Quality【质量】
Evaluated by Immunocytochemistry in undifferentiated ReNcell VM neural progenitor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in undifferentiated ReNcell VM neural progenitor cells.
Physical form【外形】
Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Analysis Note【分析说明】
Control
Undifferentiated ReNcell VM neural progenitor cells
Legal Information【法律信息】
ALEXA FLUOR is a registered trademark of Life Technologies
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
ALEXA FLUOR® 488
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
NCBI accession no.【NCBI登记号】
NP_003097
UniProt accession no.【UniProt登记号】
P48431
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
The unconjugated antibody (AB5603) tested on western blot detects Sox2 in whole cell or nuclear extracts as a protein band at 34 kDa
Storage and Stability【储存及稳定性】
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
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