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Anti-NG2, Alexa Fluor®488 Conjugate Antibody

产品编号:4082418
规格:from rabbit, ALEXA FLUOR® 488
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4082418100 μL7190
产品别名

Anti-NG2, Alexa Fluor®488 Conjugate Antibody

Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
NG2 is a high molecular weight, integral membrane chondroitin sulfate proteoglycan. It is found on the surfaces of an unusual class of glial cells within the developing and mature central nervous system that have the properties of oligodendrocyte precursor cells (i.e., O-2A progenitor cells). NG2 is also found on the surfaces of chondroblasts, proliferating capillary endothelial cells, some human melanoma cell lines, and on leukemic blasts in childhood acute lymphoblastic leukemia. The NG2 proteoglycan is likely to play a role in regulation of cell motility, axon outgrowth and the cellular responses to platelet-derived growth factor.
Specificity【特异性】
This antibody identifies the intact proteoglycan and core protein by WB and ELISA. When oligodendrocyte precursor cells (i.e. O-2A progenitor cells) are stained alive, the stain appears as clusters on the cell surface. This antibody does not stain differentiated oligodendrocytes well.
Immunogen【免疫原】
Immunoaffinity purified NG2 Chondroitin Sulfate Proteoglycan from rat
Application【应用】
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in adult rat brain tissue.
Research Category
Neuroscience
Anti-NG2, Alexa Fluor®488 Conjugate Antibody detects level of NG2 & has been published & validated for use in ICC & IHC.
Research Sub Category
Neurodegenerative Diseases
Quality【质量】
Evaluated by Immunocytochemistry in rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.
Physical form【外形】
Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein A adsorption
Analysis Note【分析说明】
Control
Rat oligodendrocyte precursor cells
Legal Information【法律信息】
ALEXA FLUOR is a registered trademark of Life Technologies
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
ALEXA FLUOR® 488
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
rat
species reactivity (predicted by homology)
monkey (based on 100% sequence homology), mouse (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI accession no.【NCBI登记号】
NP_001888
UniProt accession no.【UniProt登记号】
Q6UVK1
shipped in【运输】
wet ice
产品说明
Target description【目标描述】
The unconjugated parent antibody (Cat. No. AB5320) has an observed molecular weight at ~270-300 kDa
Storage and Stability【储存及稳定性】
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 2
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