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产品别名
Anti-ERp57 Antibody
Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, 58 kDa microsomal protein, p58, Disulfide isomerase ER-60, Endoplasmic reticulum resident protein 57, ER protein 57, ERp57, Endoplasmic reticulum resident protein 60, ER protein 60, ERp60
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Endoplasmic reticulum resident protein 57 (ERp57) is also called Protein disulfide-isomerase A3 (PDIA3), 58 kDa glucose-regulated protein (GRP58), 58 kDa microsomal protein (p58), Disulfide isomerase ER-60, and Endoplasmic reticulum resident protein 60 (ERp60). ERp57 catalyzes the rearrangement of -S-S- bonds in proteins and is associated with signal transduction, nuclear protein import and apoptosis. ERp57 is expressed in the flagellum and head regions of spermatozoa. |
Immunogen【免疫原】 | Recombinant protein corresponding to human ERp57. |
Application【应用】 | Research Sub Category Transcription Factors Detect ERp57 using this rabbit polyclonal antibody, Anti-ERp57 Antibody validated for use in western blotting & Chromatin IP (ChIP). Research Category Epigenetics & Nuclear Function Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory lot detected ERp57 in M14 cell lysates (Chichiarelli, S., et al. (2010). Arch Biochem Biophys. 494(2):178-183; Chichiarelli, S., et al. (2007). J Cell Physiol. 210(2):343-351.). Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected ERp57 in NPA, WRO, ARO and NCI cell lysates (Prof. F. Altieri, University of Rome, La Sapienza). |
Quality【质量】 | Evaluated by Western Blotting in HeLa cell lysate. Western Blotting Analysis: 1:1,000 dilution of this antibody detected ERp57 in 10 µg of HeLa cell lysate. |
Physical form【外形】 | Unpurified Rabbit polyclonal in buffer containing serum with 0.05% sodium azide. |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | serum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human, mouse, rat |
technique(s) | ChIP: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_005304 |
UniProt accession no.【UniProt登记号】 | P30101 |
shipped in【运输】 | wet ice |
Gene Information | human ... PDIA3(2923) |
产品说明
Target description【目标描述】 | ~57 kDa observed |
Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |