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Anti-Nestin Antibody, clone rat-401, Cy3 conjugate
| 产品编号： | 4081833 |
| 规格： | clone rat-401, from mouse, CY3 conjugate |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Nestin Antibody, clone rat-401, Cy3 conjugate
rat401, NES, Nbla00170, FLJ21841
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells (Mokry and Nemecek, 1998). Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinomas. |
| Specificity【特异性】 | This antibody recognizes both rat and mouse Nestin. Antibody is not reactive with human Nestin protein. |
| Immunogen【免疫原】 | Embryonic rat spinal cord |
| Application【应用】 | This Anti-Nestin Antibody, clone rat-401, Cy3 conjugate is validated for use in ICC for the detection of Nestin. Research Category Stem Cell Research Neuroscience Research Sub Category Neurofilament & Neuron Metabolism Neuronal & Glial Markers |
| Quality【质量】 | Evaluated by Immunocytochemistry in mouse cortical neural stem cells (SCR029). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Nestin in mouse cortical neural stem cells (SCR029). |
| Physical form【外形】 | Purified mouse monoclonal IgG1 conjugated to Cy3 in PBS with 0.1% sodium azide and 15mg/ml BSA. Protein G Purified |
| Analysis Note【分析说明】 | Control Mouse cortical neural stem cells (SCR029) |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | CY3 conjugate |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | rat-401, monoclonal |
| species reactivity | rat, mouse |
| should not react with | human |
| technique(s) | immunocytochemistry: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NP_037119 |
| UniProt accession no.【UniProt登记号】 | P21263 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | The unconjugated parent antibody (Catalog No. MAB353) has an observed MW at 220-240 kDa |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
