纤连蛋白 溶液 来源于人类成纤维细胞

289-149-2

MFCD00131062

NA.75

Fibronectin 1 (FN1) is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35. Fibronectin is mostly synthesized by fibroblasts and endothelial cells.

Epithelial cells, mesenchymal cells, neuronal cells, fibroblasts, neural crest cells, endothelial cells
Fibronectin human foreskin fibroblasts has been used in extracellular matrix binding assay and probiglycan and cleavage assays. It has also been used in ectoderm (neuronal) differentiation and in the preparation of a semi-solid growth medium.

Fibronectin 1 (FN1) participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Fibronectin production by normal human foreskin fibroblasts has been shown to improve two-fold after glucocorticoid treatment.

本品复原后，不建议涡漩、过度搅拌、反复冻融。

Lyophilized in CAPS buffered saline

dialyzed against chloroform

Store reconstituted solution in working aliquots at -20℃ or lower.

蛋白质均一性由免疫电泳评估。

200

human foreskin fibroblasts

BioReagent

lyophilized powder

~550 kDa

cell culture | mammalian: suitable

1‑5 μg/cm²

H₂O: 1 mg/mL at 37 ℃ (Store reconstituted solution in working aliquots at -20℃ or lower.)

attachment factor, mesenchymal cell attachment, neuronal cell attachment, fibroblast attachment, neural crest cell attachment, endothelial cell attachment

P02751

dry ice

−20℃

human ... FN1(2335)

0.5 mg in serum bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)