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Interleukin-12 human

产品编号:4081529
规格:HumanKine®, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin, tested
包装规格:10 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
408152910 μG6820
产品别名

Interleukin-12 human

IL-12

基本信息
MDL number
MFCD00212975
NACRES
NA.77
Application【应用】
Interleukin-12 (IL-12) human has been used to study IL-12 mediated enhancement of IL-12Rβ2 (IL-12 receptor) expression.
Biochem/physiol Actions【生化/生理作用】
Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.
Physical form【外形】
lyophilized from a 0.2 μm filtered solution of PBS
Analysis Note【分析说明】
The specific activity was determined by the dose-dependent release of IFN-γ from the human NK92 cell line in presence of 20 ng/mL rIL-2.
Legal Information【法律信息】
HumanKine is a registered trademark of Proteintech Group, Inc.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
human
recombinant【重组】
expressed in HEK 293 cells
Assay【测定】
≥95% (SDS-PAGE)
form【形式】
lyophilized
potency【效能】
≤2 ng/mL EC50
mol wt【分子量】
dimer 57 kDa (glycosylated)
packaging【包装】
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities【杂质】
endotoxin, tested
storage temp.【储存温度】
−20℃
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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