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Interleukin-5 human

产品编号:4081526
规格:recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture
包装规格:5 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40815265 μG1670
产品别名

Interleukin-5 human

IL-5

基本信息
MDL number
MFCD00163946
NACRES
NA.32
Biochem/physiol Actions【生化/生理作用】
IL-5 (interleukin-5) is a maturation and differentiation factor for eosinophils. Thus, it is associated with allergy and related disorders. IL-5 association with its receptor causes activation of MEK/ERK (mitogen activated protein kinase kinase/extracellular-regulated kinase), p38 MAPK (mitogen activated protein kinase) and JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathways.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.1 mg bovine serum albumin.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
human
recombinant【重组】
expressed in baculovirus infected Sf21 cells
Assay【测定】
≥97% (SDS-PAGE)
form【形式】
lyophilized powder
potency【效能】
0.1-0.5 ng/mL EC50
mol wt【分子量】
32-34 kDa
packaging【包装】
pkg of 5 μg
concentration【浓度】
0.5-10 ng/mL
technique(s)
cell culture | mammalian: suitable
impurities【杂质】
endotoxin, tested
UniProt accession no.【UniProt登记号】
P05113
storage temp.【储存温度】
−20℃
Gene Information
human ... IL5(3567)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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