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Anti-TRPC1 antibody produced in rabbit

产品编号:4081069
规格:affinity isolated antibody, lyophilized powder
包装规格:0.05 ML,0.2 ML
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40810690.05 ML3580
40810690.2 ML4730
产品别名

Anti-TRPC1 antibody produced in rabbit

Trpc1 Antibody

Anti-Transient receptor potential cation channel, subfamily C, member 1

Trpc1 Antibody-Anti-TRPC1 antibody produced in rabbit

基本信息
MDL number
MFCD02686004
NACRES
NA.41
General description【一般描述】
Transient receptor potential cation channel subfamily C member 1 (TRPC1) is encoded by the gene mapped to human chromosome 3q22-24. The encoded protein is a member of the transient receptor potential (TRP) superfamily of cation channels and is distributed in both glomeruli and glomerular mesangial cells.
Immunogen【免疫原】
Synthetic protein corresponding to amino acids 557-571 of human TRPC1 (GenBank® Accession No. P48995). The epitope is identical in mouse and rat and highly homologous in bovine and Xenopus.
Biochem/physiol Actions【生化/生理作用】
Transient receptor potential cation channel subfamily C member 1 (TRPC1) facilitates Ca2+ entry upon store depletion in a variety of cell types by forming a multimeric complex with other TRPCs. The encoded protein is implicated in the odontoblast-like differentiation of human dental pulp cells (hDPCs). Mutation in the gene is associated with the development type 2 diabetes mellitus (T2D). Decreased expression of the gene leads to hepatocellular carcinoma cell proliferation and thus, TRPC1 can be considered as a potential therapeutic target for hepatocellular carcinoma.
Physical form【外形】
Lyophilized at 0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.
Legal Information【法律信息】
GenBank is a registered trademark of United States Department of Health and Human Services
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
rat
technique(s)
immunohistochemistry: suitable
western blot (chemiluminescent): suitable
UniProt accession no.【UniProt登记号】
Q9QX01
storage temp.【储存温度】
−20℃
Gene Information
human ... TRPC1(7220)
mouse ... Trpc1(22063)
rat ... Trpc1(89821)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Pictograms【象形图】
GHS06,GHS09
Signal word【警示用语:】
Danger
Hazard Statements
H301 + H311 - H411
Precautionary Statements
P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P391 - P501
Hazard Classifications【危险分类】
Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Chronic 2
Supp Hazards【补充剂危害】
EUH032
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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