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Anti-Guinea Pig IgG (whole molecule)-Peroxidase antibody produced in goat
产品编号: | 4077489 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 1 ML |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD00162368 |
NACRES | NA.46 |
General description【一般描述】 | IgG consists of four sub-classes, like IgG1, IgG2, IgG3, and IgG4. IgG is composed of four polypeptide chains-two heavy chains (γ chains) and two light chains (κ or λ chains) which are linked by inter-chain disulfide bonds. The heavy chains consist of a N-terminal variable domain (VH) and three constant domains (CH1, CH2, CH3). A hinge region exists between the CH1 and CH2 region. The light chains have one N-terminal variable domain (VL) and one constant domain (CL). |
Immunogen【免疫原】 | Purified guinea pig IgG |
Application【应用】 | Anti-H. pylori IgGs in guinea pig sera was measured by ELISA using HRP-conjugated goat anti-guinea pig IgG (A 7289) at a dilution of 1:2000 in 1% BSA/PBS for 1 hour at 37℃. Anti-Guinea Pig IgG (whole molecule)-Peroxidase antibody is suitable for use in immunocytochemistry and ELISA. |
Biochem/physiol Actions【生化/生理作用】 | IgGs are glycoprotein antibodies that modulate several immune responses. It plays a major role in providing immunity to the infant from the mother via the placenta. IgG activates the complement system and regulates the antibody-dependent cell-mediated cytotoxicity (ADCC). Guinea pig IgGs against target proteins are often used as primary antibodies in various research applications. Thus, secondary anti-guinea pig IgGs conjugated to detectable substrates are useful tools for the analysis of target proteins. Anti-Guinea Pig IgG (whole molecule)-Peroxidase antibody is specific for guinea pig IgG. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with preservative. |
Preparation Note【制备说明】 | Antiserum is developed in goat using purified guinea pig IgG as the immunogen. Antibody is isolated from goat anti-guinea pig IgG antiserum by immunospecific purification which removes essentially all goat serum proteins, including immunoglobulins that do not specifically bind to guinea pig IgG. Goat anti-guinea pig IgG is conjugated to Sigma Horseradish Peroxidase, Type VI (Product No. P 8375) by a modification of the periodate method of Wilson and Nakane. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | peroxidase conjugate |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | secondary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
technique(s) | direct ELISA: 1:10,000 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 1 mL in glass bottle |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS07,GHS09 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H315 - H317 - H319 - H411 |
Precautionary Statements | P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 |
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |