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α-Synuclein, Human, Recombinant, E. coli
产品别名
α-Synuclein, Human, Recombinant, E. coli
NACP
产品性质
Assay【测定】 | ≥95% (SDS-PAGE) |
Quality Level【质量水平】 | 100 |
form【形式】 | liquid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 200 μg in Plastic ampoule Please refer to vial label for lot-specific concentration. |
基本信息
General description【一般描述】 | Recombinant, human α-synuclein expressed in E. coli. An acidic neuronal protein consisting of 140 amino acids that has been implicated in the pathogenesis of Parkinson′s disease and related neurodegenerative disorders. Also reported to be an important regulatory component of vesicular transport in neuronal cells. The apparent molecular weight by SDS-PAGE is ~19-20 kDa. Recombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140). This enzyme has been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. |
Warning【警告】 | Toxicity: Standard Handling (A) |
Physical form【外形】 | In 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5. |
Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). |
Other Notes【其他说明】 | Kahle, P.J, et al. 2001. Am. J. Pathol.159, 2215. Kim, J. 1997. Mol. Cells7, 78. Paik, S.R. 1997. Arch. Biochem. Biophys.344, 325. Jakes, R., et al. 1994. FEBS Lett.345, 27. Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA90, 11282. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |