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Hydroxy-PEG6-t-butyl ester

产品编号:4075011
规格:≥95%
CAS NO:361189-64-2
包装规格:250 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4075011250 MG1510
产品别名

361189-64-2

Hydroxy-PEG6-t-butyl ester

tert-Butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate

HO-PEG6-CO-OtBu

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H38O9
Molecular weight
410.50
Application【应用】
This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Other Notes【其他说明】
Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMR

Maleimide-oligo(ethylene glycol) Derivatives of Camptothecin as Albumin-Binding Prodrugs: Synthesis and Antitumor Efficacy
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
Assay【测定】
≥95%
form【形式】
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index【折射率】
n/D 1.454
density
1.068
storage temp.【储存温度】
−20℃
SMILES string
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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