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Hydroxy-PEG6-t-butyl ester
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4075011 | 250 MG | 1510 |
产品别名
361189-64-2
Hydroxy-PEG6-t-butyl ester
tert-Butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate
HO-PEG6-CO-OtBu
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H38O9 |
Molecular weight | 410.50 |
Application【应用】 | This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation. |
Other Notes【其他说明】 | Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMR Maleimide-oligo(ethylene glycol) Derivatives of Camptothecin as Albumin-Binding Prodrugs: Synthesis and Antitumor Efficacy |
Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
Assay【测定】 | ≥95% |
form【形式】 | liquid |
reaction suitability | reagent type: cross-linking reagent |
refractive index【折射率】 | n |
density | 1.068 |
storage temp.【储存温度】 | −20℃ |
SMILES string | O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 3 |