Allyl-poly(ethylene glycol)

C₃H₅(C₂H₄O)_nOH

MFCD00020607

NA.23

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

This heterobifunctional PEG has an allyl functionality on one end and an alcohol on the other. The allyl is commonly used in thiol-ene click chemistry; as well as other ligation reactions.

powder or solid

PEG ~5,000 Da
average M_n 5,000

off-white to pale yellow

<1.3

2-8℃

13 - Non Combustible Solids

WGK 3