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GSK-3 Inhibitor XIII-CAS 404828-08-6-Calbiochem
产品编号: | 4073842 |
规格: | The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
CAS NO: | 404828-08-6 |
包装规格: | 1 MG,5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
404828-08-6
GSK-3 Inhibitor XIII-CAS 404828-08-6-Calbiochem
(5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
基本信息
Empirical Formula【经验(实验)分子式】 | C18H15N5 |
Molecular weight | 301.35 |
General description【一般描述】 | A potent and ATP-competitive inhibitor of GSK-3 (Ki = 24 nM). An aminopyrazole compound that acts as a potent and ATP-binding site inhibitor of GSK-3 with a Ki of 24 nM. |
Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Primary Target GSK-3 Cell permeable: no Target Ki: 24 nM against GSK-3 |
Warning【警告】 | Toxicity: Carcinogenic / Teratogenic (D) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
Other Notes【其他说明】 | Pierce, A.C., et al. 2005. J. Med. Chem.48, 1278. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | white |
solubility【溶解性】 | DMSO: 5 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
packaging【包装】 | 1, 5 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |