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IgG1 同种型对照 来源于鼠骨髓瘤
IgG1-FITC Isotype Control from murine myeloma
产品编号: | 4067573 |
规格: | clone MOPC 21, purified immunoglobulin, buffered aqueous solution |
包装规格: | 0.1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
IgG1 同种型对照 来源于鼠骨髓瘤
IgG1-FITC Isotype Control from murine myeloma
IgG1 Isotype Control from murine myeloma
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | FITC conjugate |
antibody form【抗体形式】 | purified immunoglobulin |
clone【克隆】 | MOPC 21, monoclonal |
form【形式】 | buffered aqueous solution |
storage condition【储存条件】 | protect from light |
technique(s) | flow cytometry: suitable |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
基本信息
General description【一般描述】 | Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3. |
Application【应用】 | IgG1?FITC Isotype Control from murine myeloma has been used in flow cytometry and as a negative staining control. IgG1-FITC Isotype Control from murine myeloma was used as negative control in FACS of human erythroid cell population that is expresses CD17. |
Biochem/physiol Actions【生化/生理作用】 | Immunoglobulin G (IgG) plays a major role in hypersensitivity type II and type III reactions. IgG is also involved in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide. |
Preparation Note【制备说明】 | Prepared by conjugation to fluorescein isothiocyanate isomer I (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm. |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |