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Anti-phospho-S6-Kinase (pThr389) antibody produced in rabbit
| 产品编号： | 4063707 |
| 规格： | affinity isolated antibody, buffered aqueous glycerol solution |
| 包装规格： | 0.1 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-phospho-S6-Kinase (pThr389) antibody produced in rabbit
Anti-phospho-p70S6K (pThr389)
基本信息
| MDL number | MFCD02097170 |
| NACRES | NA.44 |
| General description【一般描述】 | p70 S6 kinase or p70S6K is a protein that belongs to Ser/Thr protein kinase family. It has a crucial role in cell growth and G1 cell cycle progression. It also has a pivotal role in phosphorylating eEF2k at a conserved serine residue and hence regulating the protein synthesis. Rabbit anti-phospho-(p70S6K) antibody can identify p70 S6 kinase and p85 S6 kinase when phosphorylated at (Thr389). Anti-phospho-S6-kinase (pThr389) antibody reacts specifically with p70 S6 kinase of rat, mouse and human. This product can also detect few phosphorylated isoforms of Protein Kinase C when present at high level in cells. |
| Immunogen【免疫原】 | A synthetic phospho-(Thr389) peptide corresponding to residues around (Thr389) of human p70 S6 kinase, coupled to KLH. |
| Application【应用】 | Anti-phospho-S6-kinase (pThr389) antibody can be used in western blotting (chemiluminescent) (diluted 1:1000) using serum-treated NIH3T3 cell extract or insulin-treated HeLa, COS, and C6 cell extracts. |
| Physical form【外形】 | Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous glycerol solution |
| species reactivity | rat, human, mouse |
| technique(s) | western blot (chemiluminescent): 1:1,000 using serum-treated NIH3T3 cell extract, or insulin-treated HeLa, COS, and C6 cell extracts |
| UniProt accession no.【UniProt登记号】 | P23443 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RPS6KB1(6198) mouse ... Rps6kb1(72508) rat ... Rps6kb1(83840) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
