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Anti-phospho-Retinoblastoma (pSer807) antibody produced in rabbit
| 产品编号： | 4063522 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 1 VIAL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-phospho-Retinoblastoma (pSer807) antibody produced in rabbit
Anti-phospho-Rb (pSer807)
基本信息
| MDL number | MFCD06411895 |
| NACRES | NA.41 |
| General description【一般描述】 | RB1 (RB transcriptional corepressor 1) codes for nuclear phosphoprotein pRB (retinoblastoma protein). It is located on chromosome 13q14. It is a tumor-suppressor gene. |
| Immunogen【免疫原】 | synthetic phosphopeptide derived from the region of human Rb that contains Ser807. |
| Biochem/physiol Actions【生化/生理作用】 | RB1 (RB transcriptional corepressor 1) plays an important role throughout G1/S phase transition. Absence of RB induces prostate cancer metastasis. It plays an important role in modulating the cell cycle. It also regulates cell stemness and differentiation. |
| Physical form【外形】 | Solution in phosphate buffer, pH 7.4, containing 1 mg/mL BSA (protease and IgG-free) and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | western blot: 0.25-0.75 μg/mL using Jurkat cells in high growth phase. |
| UniProt accession no.【UniProt登记号】 | P06400 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... RB1(5925) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
