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CID755673
产品编号: | 3425906 |
规格: | ≥98% (HPLC), powder |
CAS NO: | 521937-07-5 |
包装规格: | 5 MG,25 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3425906 | 5 MG | 1660 | |||
3425906 | 25 MG | 6090 |
产品别名
521937-07-5
CID755673
7-Hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one
2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C12H11NO3 |
Molecular weight | 217.22 |
MDL number | MFCD03828155 |
PubChem Substance ID【PubChem化学物质编号】 | 329825080 |
NACRES | NA.77 |
Application【应用】 | CID755673 was used to study the role of PKD in dendrite retraction in mouse Purkinje cells. |
Biochem/physiol Actions【生化/生理作用】 | CID755673 is a cell-permeable, potent and selective inhibitor of all three protein kinase D (PKD) isoforms PKD1 (PKCμ), PKD2, and PKD3 (PKCν). CID755673 is not competitive with ATP. CID755673 was not suitable to inhibit PKD in Swiss 3T3 cells as it utilizes PKD-dependent pathway to enhance the mitogenic signaling triggered by EGF, phorbol esters and bombesin. It should, therefore, be used with caution. |
Features and Benefits【特点和优势】 | This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to tan |
solubility【溶解性】 | DMSO: ≥15 mg/mL |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Oc1ccc2oc3C(=O)NCCCc3c2c1 |
InChI | 1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15) |
InChI key | AACFPJSJOWQNBN-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |