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CASIN

产品编号:3423566
规格:≥98% (HPLC)
CAS NO:425399-05-9
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
34235665 MG1530
342356625 MG5620
产品别名

425399-05-9

CASIN

2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol

Cdc42 Activity-Specific Inhibitor

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C20H22N2O
Molecular weight
306.40
MDL number
MFCD01853271
PubChem Substance ID【PubChem化学物质编号】
329825745
Application【应用】
CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:
  • to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
  • to study its effects on mice jejunum
  • to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice

Biochem/physiol Actions【生化/生理作用】
CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo..
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
, white to very dark brown
solubility【溶解性】
DMSO: 20 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3
InChI
1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2
InChI key
RXIUMAOXORBRCY-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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