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CASIN
产品别名
425399-05-9
CASIN
2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
Cdc42 Activity-Specific Inhibitor
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C20H22N2O |
Molecular weight | 306.40 |
MDL number | MFCD01853271 |
PubChem Substance ID【PubChem化学物质编号】 | 329825745 |
Application【应用】 | CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:
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Biochem/physiol Actions【生化/生理作用】 | CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | , white to very dark brown |
solubility【溶解性】 | DMSO: 20 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3 |
InChI | 1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2 |
InChI key | RXIUMAOXORBRCY-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |