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Caged MK801
产品别名
217176-91-5
Caged MK801
Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate
10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
cMK801
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H24N2O6 |
| Molecular weight | 460.48 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825309 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Caged MK801 is an inactive caged form of the potent selective non-competitive irreversible NMDA glutamate receptor open-channel blocker MK801. Caged MK801 is cleaved by exposure to UV light, liberating the active MK801. The caged compound is stable within cells. Intracellular compartment-specific photorelease allowed study the locus of induction and expression of timing-dependent long-term depression (t-LTD). Caged MK801 is thus a useful tool to uncover compartment-specific biological functions. |
| Features and Benefits【特点和优势】 | This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white to light yellow |
| solubility【溶解性】 | DMSO: ≥10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1cc(COC(=O)N2[C@@H]3Cc4ccccc4[C@@]2(C)c5ccccc35)c(cc1OC)[N+]([O-])=O |
| InChI | 1S/C26H24N2O6/c1-26-19-10-6-4-8-16(19)12-22(18-9-5-7-11-20(18)26)27(26)25(29)34-15-17-13-23(32-2)24(33-3)14-21(17)28(30)31/h4-11,13-14,22H,12,15H2,1-3H3/t22-,26+/m1/s1 |
| InChI key | WZDXUEMCALAOAY-GJZUVCINSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
