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BVT.2733
产品别名
376640-41-4
BVT.2733
1-[[2-[[(3-Chloro-2-methylphenyl)sulfonyl]amino]-4-thiazolyl]acetyl]-4-methyl-piperazine
3-Chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]-benzenesulfonamide
BVT 2733
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H21ClN4O3S2 |
| Molecular weight | 428.96 |
| MDL number | MFCD13152134 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825717 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | BVT.2733 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that protects osteoblasts against endogenous glucocorticoid induced dysfunction. BVT.2733 lowers blood glucose levels in in hyperglycaemic mice. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to light brown |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=S(C1=C(C)C(Cl)=CC=C1)(NC2=NC(CC(N3CCN(C)CC3)=O)=CS2)=O |
| InChI | 1S/C17H21ClN4O3S2/c1-12-14(18)4-3-5-15(12)27(24,25)20-17-19-13(11-26-17)10-16(23)22-8-6-21(2)7-9-22/h3-5,11H,6-10H2,1-2H3,(H,19,20) |
| InChI key | YDPRNGAPPNPYQQ-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
