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BRD7389
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3420246 | 5 MG | 2280 |
产品别名
376382-11-5
BRD7389
1-[(2-Phenylethyl)amino]-naphtho-3H-[1,2,3-de]quinoline-2,7-dione
1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione
基本信息
Empirical Formula【经验(实验)分子式】 | C24H18N2O2 |
Molecular weight | 366.41 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | BRD7398 is a RSK kinase inhibitor that induces insulin expression and differentiation of pancreatic alpha into beta cells. BRD7398 inhibits RSK1, RSK2 and RSK3; IC50 values of 1.5, 2.4 and 1.2 uM, respectively. Treatment of mouse aTC1 cells with BRD7398 induced expression of b-cell markers Pdx1, Pax4, Iapp and Npy and also induced insulin production. |
Features and Benefits【特点和优势】 | This compound is featured on the MAPKAPs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | orange |
solubility【溶解性】 | DMSO: >20 mg/mL |
storage temp.【储存温度】 | 2-8℃ |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |