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BRD7389

产品编号:3420246
规格:≥98% (HPLC)
CAS NO:376382-11-5
包装规格:5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34202465 MG2280
产品别名

376382-11-5

BRD7389

1-[(2-Phenylethyl)amino]-naphtho-3H-[1,2,3-de]quinoline-2,7-dione

1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione

基本信息
Empirical Formula【经验(实验)分子式】
C24H18N2O2
Molecular weight
366.41
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
BRD7398 is a RSK kinase inhibitor that induces insulin expression and differentiation of pancreatic alpha into beta cells. BRD7398 inhibits RSK1, RSK2 and RSK3; IC50 values of 1.5, 2.4 and 1.2 uM, respectively. Treatment of mouse aTC1 cells with BRD7398 induced expression of b-cell markers Pdx1, Pax4, Iapp and Npy and also induced insulin production.
Features and Benefits【特点和优势】
This compound is featured on the MAPKAPs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
orange
solubility【溶解性】
DMSO: >20 mg/mL
storage temp.【储存温度】
2-8℃
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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