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BM(PEG)2 (1,8-双马来酰亚胺基-二甘醇)

BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
产品编号:3415639
包装规格:50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
341563950 MG1410
产品别名

BM(PEG)2 (1,8-双马来酰亚胺基-二甘醇)

BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H16N2O6
Molecular weight
308.29
MDL number
MFCD01096749
PubChem Substance ID【PubChem化学物质编号】
329768819
NACRES
NA.22
General description【一般描述】
BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
Features and Benefits【特点和优势】
  • Reactive groups: maleimide (both ends)
  • Reactive towards: sulfhydryl groups
  • Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 2-unit polyethylene glycol spacer arm
  • PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
  • Ideal for small molecule or peptide conjugations
Caution【注意】
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥90%
form【形式】
powder
mol wt【分子量】
308.29
reaction suitability
reagent type: cross-linking reagent
storage condition【储存条件】
desiccated
solubility【溶解性】
water: soluble
shipped in【运输】
ambient
storage temp.【储存温度】
2-8℃
SMILES string
O=C(C=CC1=O)N1CCOCCOCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-11-1-2-12(18)15(11)5-7-21-9-10-22-8-6-16-13(19)3-4-14(16)20/h1-4H,5-10H2
InChI key
FERLGYOHRKHQJP-UHFFFAOYSA-N
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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