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白桦脂酸

Betulinic Acid
产品编号:3413976
规格:≥98% (HPLC)
CAS NO:472-15-1
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34139765 MG783
341397625 MG2050
产品别名

472-15-1

白桦脂酸

Betulinic Acid

Mairin

Lupatic acid

3β-Hydroxy-20(29)-lupaene-28-oic acid

卢帕酸

丁子香萜

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C30H48O3
Molecular weight
456.70
EC number【EC 号】
207-448-8
MDL number
MFCD00009619
PubChem Substance ID【PubChem化学物质编号】
329773146
NACRES
NA.25
General description【一般描述】
Betulinic acid (BetA) is a natural product mostly sourced from the birch tree (Betula spp.). This pentacyclic lupanetype triterpenoid is also associated with other species such as Syzygium spp., Diospyros spp., Ziziphus spp., and Paeonia spp..
Application【应用】
Betulinic acid (BetA) has been used:
  • to test its effects as an antiviral agent against Dengue virus (DENV)
  • as a sterol regulatory element-binding protein (SREBP) inhibitor to repress the lipid metabolism and proliferation of clear cell renal cell carcinoma (ccRCC) cells
  • as a treatment to test its anti-tumor properties for cell viability and apoptotic cell death assays in multiple myeloma models

Biochem/physiol Actions【生化/生理作用】
Betulinic acid displays many biological and pharmacological properties such as anticancer, anti-inflammatory, anti-bacterial, anti-human immunodeficiency virus (HIV), and anti-malarial properties.
桦木酸是一种五环三萜类化合物,通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
mp
295-298 ℃ (dec.) (lit.)
storage temp.【储存温度】
2-8℃
SMILES string
CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI
1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI key
QGJZLNKBHJESQX-FZFNOLFKSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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