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Anti-ZBED3 antibody produced in rabbit
| 产品编号： | 3406325 |
| 规格： | affinity isolated antibody, buffered aqueous solution, ab1 |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ZBED3 antibody produced in rabbit
Anti-Zinc finger BED-type domain containing 3
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | ZBED3 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP3500028. |
| Physical form【外形】 | Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | predicted mol wt 26 kDa |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable indirect ELISA: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_115743 |
| UniProt accession no.【UniProt登记号】 | Q96IU2 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ZBED3(84327) |
产品说明
| Target description【目标描述】 | Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
