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Anti-UTX antibody produced in rabbit
产品别名
Anti-UTX antibody produced in rabbit
Anti-DKFZp686A03225
Anti-MGC141941
Anti-BA386N14.2
Anti-Ubiquitously transcribed tetratricopeptide repeat, X chromosome
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 154 kDa |
| species reactivity | mouse, dog, rat, bovine, rabbit, human, guinea pig, horse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O15550 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... UTX(7403) |
基本信息
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human UTX |
| Biochem/physiol Actions【生化/生理作用】 | UTX is a histone demethylase that specifically demethylates ′Lys-27′ of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 ′Lys-27′. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of ′Lys-27′ of histone H3 is concomitent with methylation of ′Lys-4′ of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. |
| Sequence【序列】 | Synthetic peptide located within the following region: KTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
