Anti-TNFSF12 antibody produced in rabbit

MFCD02095846

Tumour necrosis factor superfamily member 12 (TNFSF), formerly known as TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a soluble cytokine ligand. TNFSF signals through a transmembrane protein receptor, fibroblast growth factor-inducible 14 (Fn14). In human chromosome the gene TNFSF is localized on 17p13.1.

Synthetic peptide directed towards the N terminal region of human TNFSF12

TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. The elevated levels of TNFSF is pathologically significant in case of rheumatoid arthritis, multiple sclerosis, lupus nephritis in kidney. etc.,

Synthetic peptide located within the following region: LGLLLAVVSLGSRASLSAQEPAQEELVAEEDQDPSELNPQTEESQDPAPF

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

17 kDa

human

0.5 mg - 1 mg/mL

western blot: suitable

O43508

wet ice

−20℃

human ... TNFSF12(8742)

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12 - Non Combustible Liquids

WGK 3