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Anti-TMPRSS11D antibody produced in rabbit
产品别名
Anti-TMPRSS11D antibody produced in rabbit
Anti-MGC150588
Anti-HAT
Anti-MGC150587
Anti-Transmembrane protease, serine 11D
基本信息
| MDL number | MFCD02262999 |
| NACRES | NA.41 |
| General description【一般描述】 | Transmembrane serine protease 11D (TMPRSS11D) also known as human airway trypsin or HAT encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. TMPRSS11D is expressed predominantly in the respiratory tract. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. In human chromosome, the gene TMPRSS11D is located on 4q13.2. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human TMPRSS11D |
| Biochem/physiol Actions【生化/生理作用】 | Transmembrane serine protease 11D (TMPRSS11D) protein may play some biological role in the host defence system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. TMPRSS11D known to facilitate the entry of influenza viruses. TMPRSS11D is a common active proteolytic enzymes in lower female reproductive tract. TMPRSS11D expression is a key marker for squamous cell carcinogenesis and non-small cell lung cancer (NSCLC). |
| Sequence【序列】 | Synthetic peptide located within the following region: IHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVC |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 46 kDa |
| species reactivity | human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O60235 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TMPRSS11D(9407) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
