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Anti-TF2E2 antibody produced in rabbit
产品别名
Anti-TF2E2 antibody produced in rabbit
TF2E2
T2EB
GTF2E2
Transcription initiation factor IIE β subunit
基本信息
NACRES | NA.41 |
General description【一般描述】 | Anti-TF2E2 Antibody detects endogenous levels of total TF2E2 protein. The gene GTF2E2 (general transcription factor IIE subunit 2) is mapped to human chromosome 8p12. The protein has a serine-rich region, a centrally located forkhead domain, a leucine repeat motif, a region similar to the bacterial σ factor subdomain 3, a bHLH (basic region-helix-loop-helix) motif and a bHL (basic region-helix-loop) sequence. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human TF2E2. Immunogen Range: 151-200 |
Biochem/physiol Actions【生化/生理作用】 | The gene GTF2E2 (general transcription factor IIE subunit 2) encodes the β subunit of transcription factor IIE (TFIIEβ). It has DNA binding ability and is essential for transcription. GTF2E2 also binds to RNA polymerase II. In patients with trichothiodystrophy, mutation in GTF2E2 is responsible for destabilization of TFIIE. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 33 kDa |
species reactivity | human, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | P29084 |
UniProt accession no.【UniProt登记号】 | P29084 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... GTF2E2(2961) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |