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Anti-SUV420H1 antibody produced in rabbit
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal of human SUV420H1. |
Biochem/physiol Actions【生化/生理作用】 | Suv420h1 is a histone methyltransferase that specifically trimethylates ′Lys-20′ of histone H4. H4 ′Lys-20′ trimethylation represents a specific tag for epigenetic transcriptional repression. It mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins. |
Sequence【序列】 | Synthetic peptide located within the following region: FINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFC |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 35 kDa |
species reactivity | rat, human, mouse, dog, bovine |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | ChIP: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_001167884 |
UniProt accession no.【UniProt登记号】 | Q3U8K7-4 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... KMT5B(51111) mouse ... Suv420h1(225888) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |