您的位置:首页 > 产品中心 > ANTI-STARD4 (N-TERM) antibody produced in rabbit
ANTI-STARD4 (N-TERM) antibody produced in rabbit
产品编号: | 3398231 |
规格: | IgG fraction of antiserum, buffered aqueous solution |
包装规格: | 400 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
ANTI-STARD4 (N-TERM) antibody produced in rabbit
StAR-related lipid transfer protein 4
STARD4
基本信息
NACRES | NA.41 |
General description【一般描述】 | StAR (steroidogenic acute regulatory protein) related lipid transfer domain containing 4 (STARD4) belongs to the StAR family of proteins containing StAR related lipid transfer (START) domain. StARD4 is ubiquitously expressed with higher level of expression in liver and kidney. In human chromosome, the gene STARD4 is localized on 5q22. |
Biochem/physiol Actions【生化/生理作用】 | StAR related lipid transfer domain containing 4 (STARD4) is regulated by sterol regulatory element binding protein-2 (SREBP-2). StARD4 is involved in regulating cholesterol metabolism, and maintaining cholesterol homeostasis. StARD4 converts cholesterol to cholesteryl esters. StARD4 is involved in the bile acid synthesis. StARD4 is capable of transporting cholesterol across the membrane. It transports cholesterol directionally to endoplasmic reticulum and endocytic recycling compartment. Mutations in StARD4 leads to decreased sterol transfer. |
Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 23517 Da |
species reactivity | human |
technique(s) | immunohistochemistry: 1:50-1:100 western blot: 1:250-1:500 |
NCBI accession no.【NCBI登记号】 | NP_631903.1 |
UniProt accession no.【UniProt登记号】 | Q96DR4 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |