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Anti-SLC2A5 antibody produced in rabbit

产品编号:3395868
规格:Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
包装规格:25 μL,100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
339586825 μL2430
3395868100 μL5840
产品别名

Anti-SLC2A5 antibody produced in rabbit

Anti-Fructose transporter antibody produced in rabbit

Anti-Glucose transporter type 5, small intestine antibody produced in rabbit

Anti-Solute carrier family 2, facilitated glucose transporter member 5 antibody produced in rabbit

基本信息
Human Protein Atlas Number【人类蛋白质图谱编号】
HPA005449    Human Protein Atlas characterization data
General description【一般描述】
Glucose transporters (GLUTs) are a family of transporters that have 12 isoforms. These isoforms differ in function, tissue distribution and developmental regulation. Solute carrier family 2, member 5 (SLC2A5), also called GLUT5 is one such isoform, which is expressed in kidney, sperm cells and small intestine. It is the only transporter in the GLUT family, which is specific for fructose and is incapable of transporting glucose or galactose. The human SLC2A5 gene encodes for a 501 amino acid protein and has 12 exons. In humans, this gene is localized to the short arm of chromosome 1.
Immunogen【免疫原】
Solute carrier family 2, facilitated glucose transporter member 5 recombinant protein epitope signature tag (PrEST)
Application【应用】
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem/physiol Actions【生化/生理作用】
Solute carrier family 2, member 5 (SLC2A5) is responsible for the transport of fructose in the lumen of small intestine, kidney, brain and other insulin responsive tissues such as adipose tissue and muscle. It might also be responsible for recapturing the fructose lost in glomerular filtration. The fructose uptake rate and the expression levels of SLC2A5 depend upon various conditions such as obesity, diabetes, hypertension and inflammation (metabolic syndrome). Carcinogenesis has been shown to induce SLC2A5 expression, especially in mammary glands.
Features and Benefits【特点和优势】
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.
Linkage【联系】
Corresponding Antigen APREST86879.
Physical form【外形】
Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
Legal Information【法律信息】
Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
product line【产品线】
Prestige Antibodies® Powered by Atlas Antibodies
form【形式】
buffered aqueous glycerol solution
species reactivity
human
packaging【包装】
antibody small pack of 25 μL
enhanced validation【增强验证】
recombinant expression
orthogonal RNAseq
Learn more about Antibody Enhanced Validation
technique(s)
immunoblotting: 0.04-0.4 μg/mL
immunohistochemistry: 1:200-1:500
immunogen sequence【免疫原序列】
KALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQ
UniProt accession no.【UniProt登记号】
P22732
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SLC2A5(6518)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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