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Anti-SLC12A2 (ab1) antibody produced in chicken

产品编号:3395465
规格:affinity isolated antibody, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
339546550 μG4730
基本信息
NACRES
NA.41
Immunogen【免疫原】
Recombinant solute carrier family 12 (sodium/potassium/chloride transporters), member 2
Immunogen Sequence: GI # 4506975, sequence 800-1000
Application【应用】
Anti-SLC12A2 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions【生化/生理作用】
The Na-K-Cl cotransporter (NKCC) is a protein that helps in the active transport of sodium, potassium, and chloride into and out of cells. It couples the movement of Na+, K+ and Cl- ions across the plasma membrane of most animal cells and plays a central role in cellular homeostasis and human physiology. The proteins play important roles in Na+ and K+ concentrations in key physiological systems, including cardiac, vascular, renal, nervous, and sensory systems. NKCC1 levels and functionality are altered in certain disease states. NKCC1 may play a role in glioma cell migration, the precise mechanism by which ion transporter contributes to Glioblastoma (GB) aggressiveness. Its expression levels are found to be significantly higher in GB and anaplastic astrocytoma tissues than in grade II glioma and normal cortex. It also plays a central role in cellular chloride homeostasis and in epithelial salt transport.
Physical form【外形】
Solution in phosphate buffered saline containing 0.02% sodium azide.
产品性质
biological source【生物来源】
chicken
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
mouse, rat, human
manufacturer/tradename
Genway 15-288-22848
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001037.1
UniProt accession no.【UniProt登记号】
P55011
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SLC12A2(6558)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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