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Anti-SIGLEC11 (N-term) antibody produced in rabbit
| 产品编号： | 3395153 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-SIGLEC11 (N-term) antibody produced in rabbit
Anti-Sialic acid-binding Ig-like lectin 11
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | SIGLECs are a family of cell surface lectins defined by shared structural motifs in the first 2 immunoglobulin (Ig)-like domains and by their ability to recognize sialic acids via the first Ig V set domain. SIGLEC11 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, this protein may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| Immunogen【免疫原】 | SIGLEC11 (NP_443116, ) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SIGLEC11. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_443116 |
| UniProt accession no.【UniProt登记号】 | Q96RL6 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SIGLEC11(114132) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
