您的位置:首页 > 产品中心 > Anti-RS1 (66-78) antibody produced in rabbit
Anti-RS1 (66-78) antibody produced in rabbit
产品编号: | 3393007 |
规格: | IgG fraction of antiserum, buffered aqueous solution |
包装规格: | 200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-RS1 (66-78) antibody produced in rabbit
Anti-RS
Anti-Retinoschisin 1
Anti-XLRS1
基本信息
NACRES | NA.41 |
General description【一般描述】 | Retinoschisin 1 (RS1) is a localized in the retina and pineal. Its is encoded by the X-linked retinoschisis (XLRS) gene and is 24 kDa. It consists of a signal sequence, RS1 domain, discoidin domain and a C-terminal domain. It is secreted by the retinal neurons as a homo-octameric complex. |
Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 66-78 of human RS1 |
Application【应用】 | Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if. |
Biochem/physiol Actions【生化/生理作用】 | Retinoschisin 1 (RS1) plays a role in binding of β-2-laminin, αβ-crystallin, phospholipid, galactose and Na/K ATPase−SARM1 (Sterile alpha and TIR motif-containing protein 1) complex. Mutations in the RS1 gene leads to a condition called as X-linked juvenile retinoschisis which leads to macular degradation in males and deterioration of vision. |
Physical form【外形】 | 0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。 |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~26 kDa |
species reactivity | human |
technique(s) | western blot: 1:500-1:2,000 |
UniProt accession no.【UniProt登记号】 | O15537 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RS1(6247) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |